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Pramoxine HCL

Pramoxine HCL

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Technical characteristics
  • BrandJIa ye
  • Country of manufactureChina
  • Concentration99 %
  • ApperanceWhite or white crystalline powder
  • MW329.86
  • MFC17H27NO3 · HCl
  • EINECS211-293-1
  • CAS Number637-58-1
  • namePramoxine HCL
Description

Pramoxine HCL

CAS Number: 637-58-1

EINECS:211-293-1

MF:C17H27NO3 · HCl

MW:329.86

analytical standard, ≥98%

Apperance:White or white crystalline powder

Function:local anaesthesia

 

Pramoxine hydrochloride COA:


Melting range

170~174°C

171.7~173.2°C

Loss on drying

≤1.0%

0.12%

Residue on ignition

≤0.1%

0.04%

Ethanol

≤0.5%

0.061%

Carbinol

≤0.3%

0.10%

Acetone

≤0.5%

Not detected

Assay

98.0%~102.0%

99.98%

Conclusion

The results conforms with USP33

 

Pramoxine hydrochloride Introduction:
1.Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic
Discovered at Abbott Laboratories in 1953 and used as an antipruritic.Chemically, it is p-n
Butoxyphenyl gammamorpholinopropyl ether hydrochloride.During research and development,
Pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially
Good topical local anesthetic agent.

2.Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by
Most mucous membranes and of a low sensitizing index in man.Like other local anesthetics,
Paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation
And conduction of nerve impulses.Depolarization and repolarization of excitable neural membranes
Is thus inhibited, leading to numbness.

Pramoxine hydrochloride Usages:
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or
Other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and
Scratches.Pramocaine and dibucaine are also common ingredients in
Over the counter hemorrhoid preparations.

2.Related Local Anesthesia Powder:

Propitocaine hydrochloride CAS:1786-81-8
Tetracaine hydrochloride CAS:136-47-0
Procaine hydrochloride CAS:51-05-8
Pramoxine hydrochloride CAS:637-58-1
Proparacaine hydrochloride CAS:5875-06-9
Benzocaine hydrochloride CAS:23239-88-5
Lidocaine hydrochloride CAS:73-78-9
Articaine hydrochloride CAS:23964-57-0
Levobupivacaine hydrochloride CAS:27262-48-2
Ropivacaine hydrochloride CAS:132112-35-7
Dibucaine hydrochloride CAS:61-12-1
Bupivacaine hydrochloride CAS:14252-80-3
Articaine CAS:23964-58-1
Benzocaine CAS:94-09-7
Lidocaine CAS:137-58-6
Tetracaine CAS:94-24-6
PROCAINE CAS:59-46-1
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